产品货号：
Z14630
中文名称：
FAM129B/NIBAN2抗体
英文名称：
Anti-FAM129B/NIBAN2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FAM129B/NIBAN2 Antibody |
| 指标别名 | bA356B19.6,C9orf88,DKFZP434H0820,FAM129B,FLJ13518,FLJ22151,FLJ22298,MEG 3,Niban like protein 1,OC58,Protein FAM129B |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | NIBAN2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human FAM129B/NIBAN2 recombinant protein (Position:K23-K561). |
| 实际分子量 | 95KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | FAM129B/Niban-like protein 1 (family with sequence similarity 129,member B) belongs to a poorly characterized family of Niban proteins that also includes FAM129A/Niban and FAM129C/Niban-like protein 2.FAM129A/Niban is implicated in the ER stress response and is upregulated at the protein level in thyroid carcinoma.FAM129C/Niban-like protein 2 is preferentially expressed in B-cells and is one of five biomarkers upregulated in whole blood from patients with colorectal carcinoma.FAM129B is broadly expressed and has been shown to be a downstream target of B-Raf in melanoma cells.Though FAM129B does not appear to regulate cell growth and division,phosphorylation of FAM129B by B-Raf is essential for the invasive potential of melanoma and non-melanoma cell lines.Deletion of FAM129B in melanoma cells significantly impairs B-Raf/MEK/Erk-dependent invasion into the extracellular matrix. |
| Uniprot ID | Q96TA1 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | niban apoptosis regulator 2 |
| 蛋白名全称 | Protein Niban 2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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